Magan Medical Clinic, Dermatology
We provide quality dermatology care with compassion. Our specialty is medical dermatology, including:
Note: Cosmetic treatments are not performed in Dermatology but instead by Magan's Medical Aesthetics Laser Center.
If you have psoriasis or hair questions, Dr. Chiang possesses special expertise. He completed fellowships in both fields at University of California, San Francisco where he saw a wide spectrum of patients (including the most severe), performed clinical trials, and published research.
We take pleasure in serving our community including Covina, West Covina, San Dimas, Rancho Cucamonga, Baldwin Park, Azusa, Glendora, Upland, El Monte, Duarte, Monrovia, Arcadia, La Puente, and Diamond Bar.
No referral is necessary if you have PPO insurance. We accept a wide range of insurance plans (unfortunately, we do not accept Medi-Cal as primary insurance, only as secondary insurance).
For appointments, please call (626) 251-1500. We look forward to serving you!
"What's New in..."
A monthly column by Dr. Chiang
What's New in Acne
Oral antibiotic treatment for moderate to severe acne is fairly common. However, we haven't had a new oral antibiotic for acne for four decades. There is now a new FDA approved antibiotic for moderate severe acne in patients at least age 9. The medication is sarecycline although it is currently only available as the brand Seysara™. It is in the tetracycline class of antibiotics, similar to minocycline and doxycycline. It comes as 60 mg, 100 mg, and 150 mg versions and is dosed at about 1.5 mg of medication per kg body weight.
It is reported to have been developed to target Cutibacterium acnes, a bacteria that plays a role in acne. It seems to be active against C. acnes that is resistant to erythromycin and clindamycin. In addition, it has a similar anti-inflammatory effect against acne to other tetracycline antibiotics. It has potential for fewer side effects due to a narrower spectrum of activity, especially with less activity against intestinal bacteria. This may lead to fewer episodes of diarrhea and antibiotic resistance.
Efficacy-wise, sarecycline treated patients had notable improvement after 3 weeks, a rate of about 22% being clear or almost clear after 12 weeks, and about a 50% reduction in inflammatory lesions after 12 weeks. There was also a reduction in non-inflammatory lesions.
Side effects were similar between the sarecycline treated patients and placebo. Treated groups had about a 25-29.3% rate of adverse effects while placebo had a 26.7-29.8% rate. Nausea, headache, and vomiting occurred in 1-5% of patients. Vaginal yeast infections occurred in 0.3-1.1% of female patients in the treated group, with none in the placebo group.
Unfortunately, insurance coverage is always a question with a brand-only medication, especially since Goodrx reports a retail price of about $1027 for a month's supply.
If you have acne or another skin condition, consider making an appointment for dermatology consultation at (626) 251-1500 to discuss your options.
Charles Chiang, MD, FAAD
For archives, click here.